Article
Similar mutant frequencies observed between pairs of monozygotic twins.
Human mutation - 1 Jan 1997
Curry J, Bebb G, Moffat J, Young D, Khaidakov M, Mortimer A, Glickman B W
Abstract excerpt
The relative contribution of both genetic and environmental factors to spontaneous mutation frequency in humans is unknown. We have investigated the contribution of genetic factors to this phenomenon by determining the in vivo mutant frequency at the hypoxanthine-guanine phosphoribosyltransferase...
Topics
- Adult
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Male
- Mutation
- T-Lymphocytes
- Twins, Monozygotic