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Article

Identification of polymorphisms and sequence variants in the human homologue of the mouse natural resistance-associated macrophage protein gene.

American journal of human genetics - 1 Apr 1995

Liu J, Fujiwara T M, Buu N T, Sánchez F O, Cellier M, Paradis A J, Frappier D, Skamene E, Gros P, Morgan K

Abstract excerpt

The most common mycobacterial disease in humans is tuberculosis, and there is evidence for genetic factors in susceptibility to tuberculosis. In the mouse, the Bcg gene controls macrophage priming for activation and is a major gene for susceptibility to infection with mycobacteria. A candidate gene for Bcg was identified by positional cloning and was designated "natural resistance-associated macrophage protein...

Topics

Alleles
Animals
Base Sequence
Carrier Proteins
Cation Transport Proteins
Chromosome Mapping
Genetic Variation
Humans
Hybrid Cells
Immunity, Innate
Iron-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Membrane Proteins

Mice

Molecular Sequence Data

Polymorphism, Genetic

Tuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 7717395
PMCID: PMC1801220

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7717395-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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