Article
The natural resistance-associated macrophage protein gene in African Americans with sarcoidosis.
American journal of respiratory cell and molecular biology - 1 Jun 2000
Maliarik M J, Chen K M, Sheffer R G, Rybicki B A, Major M L, Popovich J, Iannuzzi M C
Abstract excerpt
The histologic and clinical similarities between tuberculosis and sarcoidosis suggest a shared underlying pathophysiology. Human natural resistance-associated macrophage protein (NRAMP1), which is closely related to the mouse gene, has been associated with susceptibility to tuberculosis in some human populations. Given the importance of the Nramp1 gene in animal models of granulomatous disorders, the association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
