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Article

Structure and function of the natural-resistance-associated macrophage protein (Nramp1), a candidate protein for infectious and autoimmune disease susceptibility.

Molecular medicine today - 1 May 1996

Blackwell J M

Abstract excerpt

The ability of macrophages to become activated is central to antimicrobial immunity. Microbial stimuli can elicit a cascade of gene-inductive events mediating inflammation, elimination of the invading organism and induction of T-cell memory against reinvasion. Nramp1, a gene originally identified as Ity/Lsh/Bcg for its role in controlling Salmonella typhimurium, Leishmania donovani and Mycobacterium bovis...

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Identifiers

PMID: 8796889
DOI: 10.1016/1357-4310(96)88773-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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