Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites.

doi:10.1006/geno.1994.1458

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Article

Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites.

Genomics - 1 Sept 1994

Malo D, Vogan K, Vidal S, Hu J, Cellier M, Schurr E, Fuks A, Bumstead N, Morgan K, Gros P

Abstract excerpt

The mouse chromosome 1 locus Bcg (Ity, Lsh) controls the capacity of the tissue macrophage to restrict the replication of antigenically unrelated intracellular parasites and therefore determines the natural resistance (BCG-R, dominant) or susceptibility (BCG-S, recessive) of inbred mouse strains...

Topics

Alleles
Amino Acid Sequence
Animals
Bacterial Infections
Base Sequence
Carrier Proteins
Cation Transport Proteins
Chickens
Genes, Dominant
Genetic Predisposition to Disease
Haplotypes
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Iron-Binding Proteins

Macrophages

Membrane Proteins

Mice

Mice, Inbred Strains

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 7829102
DOI: 10.1006/geno.1994.1458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7829102-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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