Article
Genomic organization and sequence of the human NRAMP gene: identification and mapping of a promoter region polymorphism.
Molecular medicine (Cambridge, Mass.) - 1 Jan 1995
Blackwell J M, Barton C H, White J K, Searle S, Baker A M, Williams H, Shaw M A
Abstract excerpt
BACKGROUND: Murine Nramp is a candidate for the macrophage resistance gene Ity/Lsh/Bcg. Sequence analysis of human NRAMP was undertaken to determine its role in man. MATERIALS AND METHODS: A yeast artificial chromosome carrying NRAMP was subcloned and positive clones sequenced. The transcriptiona...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Carrier Proteins
- Cation Transport Proteins
- Chromosome Mapping
- Chromosomes, Artificial, Yeast
- Chromosomes, Human, Pair 2
- Cloning, Molecular
- DNA Primers
- Exons
- Female
- Genetic Linkage
- Humans