Ethnic differences of polymorphism of an immunoglobulin VH3 gene.

doi:10.1172/JCI118198

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Article

Ethnic differences of polymorphism of an immunoglobulin VH3 gene.

The Journal of clinical investigation - 1 Sept 1995

Sasso E H, Buckner J H, Suzuki L A

Abstract excerpt

The VH26 germline gene occupies two different loci, due to gene duplication, and is one of the most frequently expressed human immunoglobulin VH genes. This report identifies the alleles of each VH26 locus and describes distinct patterns of VH26 polymorphism in three ethnic groups. Oligonucleotide probes targeting VH26 were used in sequence-specific RFLP analysis of DNA from 72 Caucasians, 52 Asians, 35 American...

Topics

Alleles
Asia
Asian People
Base Sequence
Black People
Chromosomes, Human, Pair 14
DNA
DNA Primers
Electrophoresis, Agar Gel
Ethnicity
Family
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Immunoglobulin

Humans

Immunoglobulin Heavy Chains

Immunoglobulin Variable Region

Leukocytes

Male

Source

Open in PubMed Open full text

Identifiers

PMID: 7657830
DOI: 10.1172/JCI118198
PMCID: PMC185785

Genes

CDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7657830-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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