Article
Genetic diversity of the human immunoglobulin heavy chain VH region.
Immunological reviews - 1 Dec 2002
Li Honghua, Cui Xiangfeng, Pramanik Sreemanta, Chimge Nyam-Osor
Abstract excerpt
The human immunoglobulin heavy chain VH region is one of the most complex regions in the human genome. The high level of diversity of this region has been shown by a number of studies. However, because of the limitations of the conventional experimental methods, it has been difficult to learn the extent of the diversity and the underlying mechanisms. This review describes a number of new genetic approaches...
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