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Article

A fetally expressed immunoglobulin VH1 gene belongs to a complex set of alleles.

The Journal of clinical investigation - 1 Jun 1993

Sasso E H, Willems van Dijk K, Bull A P, Milner E C

Abstract excerpt

The immunoglobulin VH gene 51p1, a member of the large VH1 gene family, is preferentially expressed by B cells in the fetus and in chronic lymphocytic leukemia (CLL) and appears to be the source for many cryoglobulin rheumatoid factors. Polymorphism of 51p1 may therefore be functionally important. We have studied the germline representation of 51p1 and closely related VH elements to establish their prevalence and...

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Source

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Identifiers

PMID: 8099917
DOI: 10.1172/JCI116468
PMCID: PMC443293

Genes

CDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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