Article
Polymorphism of the human Ig VH4 gene family.
Journal of immunology (Baltimore, Md. : 1950) - 15 May 1991
van Dijk K W, Sasso E H, Milner E C
Abstract excerpt
In this study, we analyze the human VH4 gene family and find it to exhibit a level of polymorphism similar to that of the much larger VH3 family. A cloned VH4 probe detected an average of 10 hybridizing BgIII restriction fragments in genomic DNA derived from 75 unrelated individuals and a total of 15 distinct bands. Of these 15 restriction fragments, 12 were polymorphic, as demonstrated by band absence in some...
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