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Article

Analysis of loss of heterozygosity in murine hepatocellular tumors.

Molecular carcinogenesis - 1 Jul 1995

Manenti G, De Gregorio L, Gariboldi M, Dragani T A, Pierotti M A

Abstract excerpt

Because allelotype analysis of tumors has been important in the identification of new tumor suppressor genes, here we studied loss of heterozygosity (LOH) in a well-defined animal experimental system. We analyzed spontaneous liver tumors from C3HHc x C57BL/6J (B6C3F1) mice and urethane-induced hepatocellular tumors from (C3H/He x Mus spretus) x C57BL/6JBy (HSB) interspecific mice. A total of 95 different genetic...

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Identifiers

PMID: 7619222
DOI: 10.1002/mc.2940130309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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