Motif-primed polymerase chain reaction-based allelotype of sarcomas induced by 3-methylcholanthrene in interspecific hybrid mice.

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Article

Motif-primed polymerase chain reaction-based allelotype of sarcomas induced by 3-methylcholanthrene in interspecific hybrid mice.

Oncogene - 3 Aug 1995

Dudley M E, Sundberg J P, Roopenian D C

Abstract excerpt

Loss of heterozygosity (LOH) occurs commonly in some human tumors and is thought to reflect the selective pressure exerted by tumor suppressor genes. The purpose of this study was to examine the genomic location and relative frequency of LOH of chemically induced tumors in an established mouse mo...

Topics

Alleles
Animals
Base Sequence
Chromosome Mapping
DNA Primers
Female
Genes, Tumor Suppressor
Heterozygote
Hybridization, Genetic
In Vitro Techniques
Male
Methylcholanthrene
Mice
Mice, Inbred C57BL
Molecular Sequence Data
Muridae
Polymerase Chain Reaction
Sarcoma, Experimental

Source

Open in PubMed

Identifiers

PMID: 7630636

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7630636-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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