Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Motif-primed polymerase chain reaction-based allelotype of sarcomas induced by 3-methylcholanthrene in interspecific hybrid mice.

Oncogene - 3 Aug 1995

Dudley M E, Sundberg J P, Roopenian D C

Abstract excerpt

Loss of heterozygosity (LOH) occurs commonly in some human tumors and is thought to reflect the selective pressure exerted by tumor suppressor genes. The purpose of this study was to examine the genomic location and relative frequency of LOH of chemically induced tumors in an established mouse model for chemical carcinogenesis. Twenty-four tumors were induced by subcutaneous injection of 3-methylcholanthrene into...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Heterozygote

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 7630636

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Motif-primed polymerase chain reaction-based allelotype of sarcomas induced by 3-methylcholanthrene in interspecific hybrid mice.PMID 7630636Read ↗

Analysis of loss of heterozygosity in murine hepatocellular tumors.Semantic proximity Read ↗

Allelotype analysis of mouse skin tumors using polymorphic microsatellites: sequential genetic alterations on chromosomes 6, 7, and 11.Semantic proximity Read ↗

Carcinogens induce genome-wide loss of heterozygosity in normal stem cells without persistent chromosomal instability.Semantic proximity Read ↗

Allelotype analysis of 2',3'-dideoxycytidine- and 1,3-butadiene-induced lymphomas in B6C3F1 mice.Semantic proximity Read ↗

Application of inter-simple sequence repeat PCR to mouse models: assessment of genetic alterations in carcinogenesis.Semantic proximity Read ↗

Allelotype analysis of chemically induced squamous cell carcinomas in F(1) hybrids of two inbred mouse strains with different susceptibility to tumor progression.Semantic proximity Read ↗

Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice.Semantic proximity Read ↗

Cancer-associated genes can affect somatic intrachromosomal recombination early in carcinogenesis.Semantic proximity Read ↗

Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability.Semantic proximity Read ↗

Elevated presence of retrotransposons at sites of DNA double strand break repair in mouse models of metabolic oxidative stress and MYC-induced lymphoma.Semantic proximity Read ↗

Allelotypic and cytogenetic characterization of chemically induced mouse mammary tumors: high frequency of chromosome 4 loss of heterozygosity at advanced stages of progression.Semantic proximity Read ↗

Allelotype analysis of mouse lung carcinomas reveals frequent allelic losses on chromosome 4 and an association between allelic imbalances on chromosome 6 and K-ras activation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.