Article
Allelotype analysis of chemically induced squamous cell carcinomas in F(1) hybrids of two inbred mouse strains with different susceptibility to tumor progression.
Carcinogenesis - 1 Jul 2000
Stern M C, Benavides F, Klingelberger E A, Conti C J
Abstract excerpt
Loss of heterozygosity (LOH) at specific chromosomal loci is generally considered indirect evidence for the presence of putative suppressor genes. Allelotyping of tumors using polymorphic markers distributed throughout the entire genome allows the analysis of specific allelic losses. In the field of chemical carcinogenesis, the outbred SENCAR mouse has been commonly used to analyze the multistage nature of skin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
