Article
High-density presentation of an immunodominant minimal peptide on B cells is MHC-linked to Th1-like immunity.
Cellular immunology - 1 Nov 1995
Murray J S, Kasselman J P, Schountz T
Abstract excerpt
Ligand-directed differences in the amount of peptide presented on a specific APC subset could influence the functional outcome of any given immune response. We have investigated this issue with a biochemically determined immunodominant peptide that is presented at a higher density on the APC of T...
Topics
- Amino Acid Sequence
- Animals
- Antigen Presentation
- B-Lymphocytes
- B7-1 Antigen
- Cell Separation
- Collagen
- Dose-Response Relationship, Immunologic
- Female
- Haplotypes
- Histocompatibility Antigens Class II
- Immunodominant Epitopes
- Lysine
- Male
- Mice
- Mice, Inbred A
- Mice, Inbred C57BL
- Molecular Sequence Data