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Article

Strand bias of ultraviolet light-induced mutations in a transcriptionally active gene in human cells.

Molecular carcinogenesis - 1 Nov 1995

Basic-Zaninovic T, Meschini R, Calcagnile A S, Palombo F, D'Errico M, Proietti-De Sanctis L, Dogliotti D, Proitti-De Sactis L

Abstract excerpt

Ultraviolet (UV)-induced repair and mutational spectra were analyzed in an inducible marker gene, the metallothionein-l/guamine-xanthine phosphoribosyl transferase (gpt) fusion gene, carried by an Epstein-Barr virus-derived shuttle vector episomically maintained in human cells. The repair rate of UV photodimers from the shuttle-vector molecules was typical of transcriptionally active sequences, 70% of the dimers...

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Identifiers

PMID: 7576114
DOI: 10.1002/mc.2940140311

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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