Article
Strand bias of ultraviolet light-induced mutations in a transcriptionally active gene in human cells.
Molecular carcinogenesis - 1 Nov 1995
Basic-Zaninovic T, Meschini R, Calcagnile A S, Palombo F, D'Errico M, Proietti-De Sanctis L, Dogliotti D, Proitti-De Sactis L
Abstract excerpt
Ultraviolet (UV)-induced repair and mutational spectra were analyzed in an inducible marker gene, the metallothionein-l/guamine-xanthine phosphoribosyl transferase (gpt) fusion gene, carried by an Epstein-Barr virus-derived shuttle vector episomically maintained in human cells. The repair rate of...
Topics
- Base Sequence
- Cell Line, Transformed
- DNA
- DNA Mutational Analysis
- DNA Repair
- Gene Deletion
- Genetic Vectors
- Genome, Human
- Humans
- Kidney
- Metallothionein
- Molecular Sequence Data
