Ultraviolet hypermutability of a shuttle vector propagated in xeroderma pigmentosum variant cells.

doi:10.1111/1523-1747.ep12371686

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Article

Ultraviolet hypermutability of a shuttle vector propagated in xeroderma pigmentosum variant cells.

The Journal of investigative dermatology - 1 Nov 1993

Waters H L, Seetharam S, Seidman M M, Kraemer K H

Abstract excerpt

Patients with the variant form of xeroderma pigmentosum (XP) have clinical XP including a high frequency of skin cancer but, in contrast to the other forms of XP, have normal post-ultraviolet (UV) DNA excision repair and nearly normal post-UV survival. However, like excision repair-deficient XP c...

Topics

Adult
Base Sequence
Cell Line
DNA Repair
Female
Genetic Vectors
Humans
Male
Molecular Sequence Data
Mutation
Plasmids
Ultraviolet Rays
Xeroderma Pigmentosum

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