Article
Enhanced secretion through the Shigella flexneri Mxi-Spa translocon leads to assembly of extracellular proteins into macromolecular structures.
Molecular microbiology - 1 Apr 1995
Parsot C, Ménard R, Gounon P, Sansonetti P J
Abstract excerpt
Genes required for entry of Shigella flexneri into epithelial cells in vitro are clustered in two adjacent loci, one of which encodes secretory proteins, the IpaA-D proteins, and the other their dedicated secretion apparatus, the Mxi-Spa translocon. Ipa secretion, which is induced upon contact of...
Topics
- Antigens, Bacterial
- Apoptosis
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Congo Red
- Extracellular Matrix Proteins
- Fimbriae, Bacterial
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Macromolecular Substances
- Mutation
- Plasmids
- Shigella flexneri
- Virulence