Article
SepA, the major extracellular protein of Shigella flexneri: autonomous secretion and involvement in tissue invasion.
Molecular microbiology - 1 Jul 1995
Benjelloun-Touimi Z, Sansonetti P J, Parsot C
Abstract excerpt
In addition to Ipa proteins and IcsA, which are involved in entry into epithelial cells and intercellular spread, respectively, Shigella secretes a 110 kDa protein, designated SepA. We report the identification, cloning, and nucleotide sequence determination of the sepA gene, analysis of SepA secretion, and construction and characterization of a sepA mutant. The sepA gene is carried by the virulence plasmid and...
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