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Article

Induction of type III secretion in Shigella flexneri is associated with differential control of transcription of genes encoding secreted proteins.

The EMBO journal - 15 May 1998

Demers B, Sansonetti P J, Parsot C

Abstract excerpt

Shigella, the etiological agent of human bacillary dysentery, invades the colonic epithelium where it induces an intense inflammatory response. Entry of Shigella into epithelial cells involves a type III secretion machinery, encoded by the mxi and spa operons, and the IpaA-D secreted proteins. In this study, we have identified secreted proteins of 46 and 60 kDa as the products of virA and ipaH9.8, respectively,...

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Identifiers

PMID: 9582283
DOI: 10.1093/emboj/17.10.2894
PMCID: PMC1170630

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Induction of type III secretion in Shigella flexneri is associated with differential control of transcription of genes encoding secreted proteins.PMID 9582283Read ↗

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A secreted anti-activator, OspD1, and its chaperone, Spa15, are involved in the control of transcription by the type III secretion apparatus activity in Shigella flexneri.Semantic proximity Read ↗

MxiE regulates intracellular expression of factors secreted by the Shigella flexneri 2a type III secretion system.Semantic proximity Read ↗

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