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Article

IpaD localizes to the tip of the type III secretion system needle of Shigella flexneri.

Infection and immunity - 1 Aug 2006

Espina Marianela, Olive Andrew J, Kenjale Roma, Moore David S, Ausar S Fernando, Kaminski Robert W, Oaks Edwin V, Middaugh C Russell, Picking William D, Picking Wendy L

Abstract excerpt

Shigella flexneri, the causative agent of shigellosis, is a gram-negative bacterial pathogen that initiates infection by invading cells within the colonic epithelium. Contact with host cell surfaces induces a rapid burst of protein secretion via the Shigella type III secretion system (TTSS). The first proteins secreted are IpaD, IpaB, and IpaC, with IpaB and IpaC being inserted into the host cell membrane to form...

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Identifiers

PMID: 16861624
DOI: 10.1128/IAI.00440-06
PMCID: PMC1539624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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IpaD localizes to the tip of the type III secretion system needle of Shigella flexneri.PMID 16861624Read ↗

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A system for identifying post-invasion functions of invasion genes: requirements for the Mxi-Spa type III secretion pathway of Shigella flexneri in intercellular dissemination.Semantic proximity Read ↗

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