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Article

Peptide-induced rescue of serologic epitopes on class I MHC molecules.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1995

Solheim J C, Carreno B M, Myers N B, Lee D R, Hansen T H

Abstract excerpt

To monitor conformational changes in MHC class I structure induced by interaction with peptide or beta 2-microglobulin (beta 2-m), we have taken a serologic approach. Previous studies by us and others have defined circumstances wherein specific peptides can decrease serologic recognition of class I molecules. However, such blocking of serologic epitopes has often been interpreted as steric hindrance by peptide...

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PMID: 7529793

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