Article
Peptide variants reveal how antibodies recognize major histocompatibility complex class I.
European journal of immunology - 1 Nov 1993
Hogquist K A, Grandea A G, Bevan M J
Abstract excerpt
The T cell receptor (TcR) on CD8+ T lymphocytes recognizes a complex which consists of a major histocompatibility complex (MHC) heavy chain, beta 2-microglobulin (beta 2M), and peptide on the surface of antigen-presenting cells. Mutational analyses have suggested that the TcR recognizes both the...
Topics
- Amino Acid Sequence
- Animals
- Antibodies
- Antibodies, Monoclonal
- Cell Line
- Genetic Variation
- H-2 Antigens
- Histocompatibility Antigens Class I
- Humans
- Mice
- Models, Biological
- Molecular Sequence Data
- Oligopeptides