Article
Effects of beta2-microglobulin mutations on the alpha-1 helical region of H2-Ld.
Immunogenetics - 1 Sept 1998
Schultz C S, Rodriguez R A, Chew E A, Dimaano C, Li F M, Santos M D, Nieto M C
Abstract excerpt
Beta-2 microglobulin (beta2m)has been shown to have an effect on the structural and functional constraints that facilitate proper class I antigen presentation. To date, no evidence has pinpointed the beta2m-specific amino acids that play an integral role in affecting structure in and around the peptide binding region of class I. To delineate beta2m amino acid positions that affect the alpha-1 helical region, we...
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