Article
Effects of beta2-microglobulin mutations on the alpha-1 helical region of H2-Ld.
Immunogenetics - 1 Sept 1998
Schultz C S, Rodriguez R A, Chew E A, Dimaano C, Li F M, Santos M D, Nieto M C
Abstract excerpt
Beta-2 microglobulin (beta2m)has been shown to have an effect on the structural and functional constraints that facilitate proper class I antigen presentation. To date, no evidence has pinpointed the beta2m-specific amino acids that play an integral role in affecting structure in and around the p...
Topics
- Amino Acid Substitution
- Amino Acids
- Animals
- Binding Sites
- Cell Line
- Epitopes
- Gorilla gorilla
- H-2 Antigens
- Histocompatibility Antigen H-2D
- Humans
- Mutation
- Protein Conformation
- Radioimmunoassay
- Recombinant Proteins
- Tumor Cells, Cultured
- beta 2-Microglobulin
