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Article

A method to quantify binding of unlabeled peptides to class I MHC molecules and detect their allele specificity.

Journal of immunological methods - 3 Feb 1993

Elvin J, Potter C, Elliott T, Cerundolo V, Townsend A

Abstract excerpt

A general method has been developed for measuring the stabilization of class I MHC molecules in extracts of the mutant cell lines .174/T2 and RMA-S. 35S-Met-labeled class I molecules which have been stabilized by peptides in vitro are immunoprecipitated with conformation dependent monoclonal antibodies and electrophoresed on polyacrylamide gels. The heavy and light chains are excised from the dried gel and...

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Identifiers

PMID: 7679131
DOI: 10.1016/0022-1759(93)90210-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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