Article
Phenotypic determinants of adenovirus E1A gene autoregulation: variable region between conserved coding domains 2 and 3.
Virology - 10 Nov 1995
Hamid R, Cogan J D, Jones S N, Tibbetts C
Abstract excerpt
Different serotypes and evolutionary variants of human adenoviruses exhibit distinctive patterns of positive and negative autoregulation of the viral E1A gene. An autoregulatory E1A promoter mutation of the adenovirus type 3 (Ad3) E1A gene renders Ad3hr15 incapable of growth in normally permissiv...
Topics
- Adenovirus E1A Proteins
- Adenoviruses, Human
- Amino Acid Sequence
- Base Sequence
- Conserved Sequence
- DNA, Viral
- Gene Expression Regulation, Viral
- Genes, Viral
- HeLa Cells
- Humans
- Molecular Sequence Data
- Phenotype
- Promoter Regions, Genetic
- Transcriptional Activation