Comparative Sequence Analysis of the Largest E1A Proteins of Human and Simian Adenoviruses

doi:10.1128/jvi.76.16.7968-7975.2002

Article

Comparative Sequence Analysis of the Largest E1A Proteins of Human and Simian Adenoviruses

28 Jul 2002

Abstract excerpt

The early region 1A (E1A) gene is the first gene expressed after infection with adenovirus and has been most extensively characterized in human adenovirus type 5 (hAd5). The E1A proteins interact with numerous cellular regulatory proteins, influencing a variety of transcriptional and cell cycle events. For this reason, these multifunctional proteins have been useful as tools for dissecting pathways regulating...

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