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Article

Map of cis-acting sequences that determine alternative pre-mRNA processing in the E3 complex transcription unit of adenovirus.

Journal of virology - 1 Oct 1992

Brady H A, Scaria A, Wold W S

Abstract excerpt

The E3 complex transcription unit of adenovirus encodes four major mRNAs (a, c, f, and h) and two minor (d and e) mRNAs with overlapping exons, alternative splice sites, and two polyadenylation sites, termed E3A (upstream) and E3B (downstream). mRNAs a and d use the E3A polyadenylation site, and mRNAs c, e, f, and h use the E3B site. We have analyzed virus mutants with deletions throughout the E3 region in order...

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Identifiers

PMID: 1388210
DOI: 10.1128/JVI.66.10.5914-5923.1992
PMCID: PMC241468

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