Article
CBF mediates adenovirus Ela trans-activation by interaction at the C-terminal promoter targeting domain of conserved region 3.
Oncogene - 1 Dec 1994
Agoff S N, Wu B
Abstract excerpt
Genetic and biochemical evidence suggest that conserved region 3 (CR3) of the adenovirus Ela polypeptide can provide two distinct and separable functions: an N-terminal transcriptional activation region and a C-terminal promoter targeting region. It is thought that the promoter targeting region o...
Topics
- Adenovirus E1A Proteins
- CCAAT-Enhancer-Binding Proteins
- Conserved Sequence
- DNA-Binding Proteins
- HSP70 Heat-Shock Proteins
- Mutation
- Promoter Regions, Genetic
- Transcription, Genetic
- Transcriptional Activation