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Article

CBF mediates adenovirus Ela trans-activation by interaction at the C-terminal promoter targeting domain of conserved region 3.

Oncogene - 1 Dec 1994

Agoff S N, Wu B

Abstract excerpt

Genetic and biochemical evidence suggest that conserved region 3 (CR3) of the adenovirus Ela polypeptide can provide two distinct and separable functions: an N-terminal transcriptional activation region and a C-terminal promoter targeting region. It is thought that the promoter targeting region of Ela CR3 interacts with promoter-specific transcription factors, thereby bringing the activation region of Ela CR3 in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 7970730

Genes

GAL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CBF mediates adenovirus Ela trans-activation by interaction at the C-terminal promoter targeting domain of conserved region 3.PMID 7970730Read ↗

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The transcriptional co-activator proteins p300 and CBP stimulate adenovirus E1A conserved region 1 transactivation independent of a direct interaction.Semantic proximity Read ↗

Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domainsSemantic proximity Read ↗

Mutational and functional analysis of an essential subdomain of the adenovirus E1A N-terminal transcription repression domain.Semantic proximity Read ↗

Suppressor mutations within the core binding factor (CBF/AML1) binding site of a T-cell lymphomagenic retrovirus.Semantic proximity Read ↗

Analysis of DNA binding by the adenovirus type 5 E1A oncoprotein.Semantic proximity Read ↗

Phenotypic determinants of adenovirus E1A gene autoregulation: variable region between conserved coding domains 2 and 3.Semantic proximity Read ↗

Transcriptional control by adenovirus E1A conserved region 3 via p300/CBP.Semantic proximity Read ↗

Functional interactions within adenovirus E1A protein complexes.Semantic proximity Read ↗

Conserved region 3 of the adenovirus type 5 DNA-binding protein is important for interaction with single-stranded DNA.Semantic proximity Read ↗

Lymphoid specific gene expression of the adenovirus early region 3 promoter is mediated by NF-kappa B binding motifs.Semantic proximity Read ↗

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