Human adenovirus type 5 variants with sequence alterations flanking the E2A gene: effects on E2 expression and DNA replication.

doi:10.1007/BF00370002

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Article

Human adenovirus type 5 variants with sequence alterations flanking the E2A gene: effects on E2 expression and DNA replication.

Virus genes - 1 Jan 1996

Caravokyri C, Leppard K N

Abstract excerpt

The human adenovirus type 5 (Ad5) E2 transcription unit is divided into a promoter-proximal region, E2A, and a distal region, E2B, each with its own polyadenylation site. Together these regions encode the three virus-derived proteins necessary for genome replication. Ad5 variants were produced th...

Topics

Adenovirus E2 Proteins
Adenovirus Infections, Human
Adenoviruses, Human
Base Sequence
DNA Replication
DNA, Viral
Gene Expression Regulation, Viral
Genes, Viral
Genetic Variation
Humans
Molecular Sequence Data
Sequence Analysis

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