Article
Growth rates of hprt and tk mutant CHO cell lines.
Mutation research - 1 Oct 1995
Jacobson B S, Morgan T L
Abstract excerpt
The growth rates of 31 X-ray-induced hypoxanthine phosphoribosyl transferase (hprt) deficient mutants of CHO-K1 cells were measured. Mutants had been classified as (1) full-deletion, (2) partial deletion or rearrangement, or (3) unchanged by Southern blot analyses. No relationship between growth rate and deletion type was observed. Even where all hprt-specific bands were missing, proliferation rates in culture...
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