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Characterization of mutants involving partial exon duplications in the hprt gene of Chinese hamster V79 cells.

Somatic cell and molecular genetics - 1 May 1996

Darè E, Zhang L H, Jenssen D

Abstract excerpt

Sequencing of hprt cDNA revealed that three spontaneous mutants in V79 Chinese hamster cells exhibit tandem duplications of exon(s), i.e., either exons 2 and 3 or exon 7. Sequences of different sizes (4.5-8 Kb) were found to be duplicated and inserted in tandem into the hprt gene. These mutants demonstrated spontaneous reversion frequencies which were about 40-fold higher than those observed with other types of...

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PMID: 8914605
DOI: 10.1007/BF02369910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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