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Article

Multiplex polymerase chain reaction-based deletion analysis of spontaneous, gamma ray- and alpha-induced hprt mutants of CHO-K1 cells.

Mutagenesis - 1 Nov 1994

Schwartz J L, Rotmensch J, Sun J, An J, Xu Z, Yu Y, Hsie A W

Abstract excerpt

Independent Chinese hamster ovary (CHO)-K1 cell mutants at the hypoxanthine-guanine phosphoribosyltransferase (hprt) locus were isolated from untreated, 60Co gamma ray- and 212Bi alpha-exposed cells and the genetic changes underlying the mutation determined by multiplex polymerase chain reaction...

Topics

Alpha Particles
Animals
Base Sequence
Bismuth
CHO Cells
Cobalt Radioisotopes
Cricetinae
Exons
Gamma Rays
Gene Frequency
Hypoxanthine Phosphoribosyltransferase
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Radioisotopes

Sequence Deletion

Source

Identifiers

PMID: 7854145
DOI: 10.1093/mutage/9.6.537

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7854145-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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