Article
Effect of growth rate on phenotypic expression of 6-thioguanine resistance in human diploid fibroblasts.
Mutation research - 1 Jan 2000
Grosovsky A J, Little J B
Abstract excerpt
The influence of growth rate on the kinetics of phenotypic expression of 6-thioguanine resistance has been investigated by establishing 3 protocols for the maintenance of mutagenized stock cultures of human diploid fibroblasts. These protocols differed in the frequency with which subculture was performed during the phenotypic expression period. The resultant growth kinetics varied widely from continual...
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