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Article

Analysis of X-ray-induced HPRT mutations in CHO cells: insertion and deletions.

Mutation research - 1 Oct 1992

Fuscoe J C, Zimmerman L J, Fekete A, Setzer R W, Rossiter B J

Abstract excerpt

Molecular alterations were examined in the hypoxanthine guanine phosphoribosyltransferase (hprt) gene of 41 independent X-ray-induced thioguanine-resistant (TGR) Chinese hamster ovary (CHO) cell clones. Rapid screening of the clones by multiplex polymerase chain reaction (PCR) for the presence or...

Topics

Animals
Base Sequence
Blotting, Southern
CHO Cells
Chromosome Inversion
Cricetinae
DNA
Exons
Gene Deletion
Hypoxanthine Phosphoribosyltransferase
Mathematics
Models, Genetic
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis

Mutagenesis, Insertional

Oligodeoxyribonucleotides

Phenotype

Polymerase Chain Reaction

Source

Identifiers

PMID: 1383700
DOI: 10.1016/0027-5107(92)90198-b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1383700-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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