Article
Live attenuated influenza vaccines in young seronegative children.
Developments in biological standardization - 1 Jan 2000
Wright P F, Kervina M, Thompson J, Torrence A E, Karzon D T
Abstract excerpt
Seronegative children undergoing primary infection sensitively reflect the residual virulence of an experimental attenuated respiratory vitral vaccine. Two temperature sensitive (ts) A/Hong Kong influenza vaccines derived following chemical mutagenesis of a cloned stock of A/Great Lakes/65 have been evaluated in vaccine trials in seronegative children. The two vaccines, ts-1[A] and ts 1[E], differ in their...
Topics
- Administration, Intranasal
- Antibodies, Viral
- Antiviral Agents
- Child, Preschool
- Humans
- Infant
- Influenza A virus
- Influenza Vaccines
- Mutation
- Vaccines, Attenuated