Use of temperature-sensitive and cold-adapted mutant viruses in immunoprophylaxis of acute respiratory tract disease.

doi:10.1093/clinids/2.3.421

Back to search

Article

Use of temperature-sensitive and cold-adapted mutant viruses in immunoprophylaxis of acute respiratory tract disease.

Reviews of infectious diseases - 1 Jan 2000

Chanock R M, Murphy B R

Abstract excerpt

Efforts currently are underway to develop mutations in the influenza A viral genome that will bring about a satisfactory level of attenuation and that can be identified by simple in vitro techniques. Two types of donor viruses that bear such mutations are being evaluated. One donor virus possesse...

Topics

Acute Disease
Adult
Child
Child, Preschool
Cold Temperature
Humans
Infant
Infant, Newborn
Influenza A virus
Influenza, Human
Mutation
Recombination, Genetic
Respiratory Syncytial Viruses
Respiratory Tract Diseases
Temperature
Viral Vaccines

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.