Article
Live fish vaccines: history and perspectives.
Developments in biological standardization - 1 Jan 1997
Benmansour A, de Kinkelin P
Abstract excerpt
In the development of live vaccines against enzootic fish viral diseases, the conventional approaches, although somewhat successful, failed finally to deliver efficient, safe, and tagged strains for vaccine application. The genetically-engineered vaccine approach also gave similarly disappointing results. Faced with these realities during our work with VHS, we turned our research effort towards understanding the...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Viral
- Bacterial Vaccines
- Fish Diseases
- Fishes
- History, 20th Century
- Molecular Sequence Data
- Mutation
- Rhabdoviridae
- Vaccines
- Viral Envelope Proteins
- Viral Vaccines
- Virulence
