Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CEBPB as a candidate mediator of DEGDB-induced tumor-associated phenotypes in colorectal cancer cells.

Ecotoxicology and environmental safety - 15 Sept 2026

Wang Jingrong, Liu Jingya, Zhu Huan, Lian Jie, Lu Haibo

Abstract excerpt

OBJECTIVE: To investigate the effects of exposure to diethylene glycol dibenzoate (DEGDB) on malignant progression in colorectal cancer (CRC) cells and to identify a prioritized candidate gene. METHODS: PubChem, SwissADME, ADMETlab 3.0, and ProTox 3.0 were used to characterize the chemical structure and predict the physicochemical and toxicological properties of DEGDB. DEGDB-related targets were retrieved from...

Read the complete abstract on PubMed

Topics

Humans
Colorectal Neoplasms
CCAAT-Enhancer-Binding Protein-beta
Cell Proliferation
Gene Expression Regulation, Neoplastic
Phenotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Cell Line, Tumor

Cell Movement

Source

Identifiers

PMID: 42617514
DOI: 10.1016/j.ecoenv.2026.120679

Genes

DGAT2
IGF2
PPARG
SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CEBPB as a candidate mediator of DEGDB-induced tumor-associated phenotypes in colorectal cancer cells.PMID 42617514Read ↗

Novel environmental contaminant 6PPD-quinone promotes malignant phenotypes in colorectal cancer cells and identifies candidate response-associated genes.Semantic proximity Read ↗

Multidimensional bioinformatics analysis reveals the potential carcinogenic role of acrylamide in colorectal cancerSemantic proximity Read ↗

Colonoid-Based Transcriptomics Reveals Conserved and Model-Specific Mechanisms of Doxorubicin-Induced Intestinal ToxicitySemantic proximity Read ↗

Unraveling the Carcinogenic Mechanisms of Food contaminants through Network Toxicology, Machine Learning, and Molecular DockingSemantic proximity Read ↗

Evaluating the Carcinogenic Potential and Molecular Mechanisms of 6PPDQ in the Human Stomach Using Organoids and Bulk Sequencing Data: A Multi-Machine Learning Approach Combined with Computational SimulationSemantic proximity Read ↗

Chemical-Induced Phenotypes at CTD Help Inform the Predisease State and Construct Adverse Outcome Pathways.Semantic proximity Read ↗

A leaky human colon model reveals uncoupled apical/basal cytotoxicity in early Clostridioides difficile toxin exposureSemantic proximity Read ↗

Single cell transcriptomics unveiled that early life BDE-99 exposure reprogrammed the gut-liver axis to promote a pro-inflammatory metabolic signature in male mice at late adulthoodSemantic proximity Read ↗

Modeling the effect of prolonged ethanol exposure on global gene expression and chromatin accessibility in normal 3D colon organoidsSemantic proximity Read ↗

COX5B-Mediated Bioenergetic Alterations Modulate Cell Growth and Anticancer Drug Susceptibility by Orchestrating Claudin-2 Expression in Colorectal CancersSemantic proximity Read ↗

The RNA-binding protein DDX39B promotes colorectal adenocarcinoma progression by stabilizing DCLK1Semantic proximity Read ↗

Investigation of Key Molecular Mechanisms of 6PPDQ in Breast Cancer Development and Progression through Network Toxicology and Computational SimulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.