Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chemical-Induced Phenotypes at CTD Help Inform the Predisease State and Construct Adverse Outcome Pathways.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Sept 2018

Davis Allan Peter, Wiegers Thomas C, Wiegers Jolene, Johnson Robin J, Sciaky Daniela, Grondin Cynthia J, Mattingly Carolyn J

Abstract excerpt

The Comparative Toxicogenomics Database (CTD; http://ctdbase.org) is a public resource that manually curates the scientific literature to provide content that illuminates the molecular mechanisms by which environmental exposures affect human health. We introduce our new chemical-phenotype module that describes how chemicals can affect molecular, cellular, and physiological phenotypes. At CTD, we operationally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Databases, Factual
Share to Drug-Related Side Effects and Adverse Reactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene-Environment Interaction

Share to Gene Ontology

Share to Phenotype

Share to Toxicogenetics

Source

Open in PubMed Open full text

Identifiers

PMID: 29846728
DOI: 10.1093/toxsci/kfy131
PMCID: PMC6111787

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chemical-Induced Phenotypes at CTD Help Inform the Predisease State and Construct Adverse Outcome Pathways.PMID 29846728Read ↗

Accessing an Expanded Exposure Science Module at the Comparative Toxicogenomics Database.Semantic proximity Read ↗

Comparative Toxicogenomics Database (CTD): update 2021.Semantic proximity Read ↗

The Comparative Toxicogenomics Database's 10th year anniversary: update 2015.Semantic proximity Read ↗

CTD tetramers: a new online tool that computationally links curated chemicals, genes, phenotypes, and diseases to inform molecular mechanisms for environmental health.Semantic proximity Read ↗

Comparative Toxicogenomics Database (CTD): update 2023.Semantic proximity Read ↗

A CTD-Pfizer collaboration: manual curation of 88,000 scientific articles text mined for drug-disease and drug-phenotype interactions.Semantic proximity Read ↗

Linking chemical data from the Comparative Toxicogenomics Database with adverse outcome pathways from the AOP-Wiki: a mechanistic data-oriented approach to help inform environmental healthSemantic proximity Read ↗

Linking chemical data from the Comparative Toxicogenomics Database with adverse outcome pathways from the AOP-Wiki: a mechanistic data-oriented approach to help inform environmental healthSemantic proximity Read ↗

Molecular annotation of AOPs guides the development of the next generation mechanistic chemical safety assessment and new approach methodsSemantic proximity Read ↗

Towards Whole Health Toxicology: In-Silico Prediction of Diseases Sensitive to Multi-Chemical ExposuresSemantic proximity Read ↗

Endocrine disrupting chemicals and COVID-19 relationships: a computational systems biology approachSemantic proximity Read ↗

From Toxicogenomics Data to Cumulative Assessment Groups: A Mechanistic Framework for Chemical GroupingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.