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Article

The RNA-binding protein DDX39B promotes colorectal adenocarcinoma progression by stabilizing DCLK1

19 Jun 2025

Abstract excerpt

DDX39B, a member of the DEAD-box (DDX) RNA helicase family, plays a pivotal role in the post-transcriptional regulation of diverse pathological processes, including tumor progression, viral replication, and neurodegenerative disorders. In this study, we investigated the functional significance of DDX39B in the proliferation and metastasis of colon adenocarcinoma (COAD) and sought to uncover its underlying...

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PMID: 40583564
DOI: 10.1093/hmg/ddaf110

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