Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

COX5B-Mediated Bioenergetic Alterations Modulate Cell Growth and Anticancer Drug Susceptibility by Orchestrating Claudin-2 Expression in Colorectal Cancers

28 Dec 2021

Abstract excerpt

Oxidative phosphorylation (OXPHOS) consists of four enzyme complexes and ATP synthase, and is crucial for maintaining physiological tissue and cell growth by supporting the main bioenergy pool. Cytochrome c oxidase (COX) has been implicated as a primary regulatory site of OXPHOS. Recently, COX subunit 5B (COX5B) emerged as a potential biomarker associated with unfavorable prognosis by modulating cell behaviors in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Ferroptosis and cancer prognosis
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35052740
DOI: 10.3390/biomedicines10010060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

COX5B-Mediated Bioenergetic Alterations Modulate Cell Growth and Anticancer Drug Susceptibility by Orchestrating Claudin-2 Expression in Colorectal CancersPMID 35052740Read ↗

Identification of COX5B as a novel biomarker in high-grade glioma patientsSemantic proximity Read ↗

Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinomaSemantic proximity Read ↗

Evaluation of the Prognostic Relevance of Differential Claudin Gene Expression Highlights Claudin-4 as Being Suppressed by TGFβ1 Inhibitor in Colorectal CancerSemantic proximity Read ↗

Identification of key claudin genes associated with survival prognosis and diagnosis in colon cancer through integrated bioinformatic analysisSemantic proximity Read ↗

Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in lung adenocarcinomaSemantic proximity Read ↗

Creatine kinase mitochondrial 2 promotes the growth and progression of colorectal cancer via enhancing Warburg effect through lactate dehydrogenase BSemantic proximity Read ↗

GTPBP4 enhances colorectal cancer cell proliferation by activating MYC-driven glycolysisSemantic proximity Read ↗

APOA5 alleviates reactive oxygen species to promote oxaliplatin resistance in PIK3CA-mutated colorectal cancer.Semantic proximity Read ↗

The expression and role of NADPH Oxidase 2 in colon cancerSemantic proximity Read ↗

The role and mechanism of claudins in cancerSemantic proximity Read ↗

Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer.Semantic proximity Read ↗

Claudin-1, A Double-Edged Sword in CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.