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Single cell transcriptomics unveiled that early life BDE-99 exposure reprogrammed the gut-liver axis to promote a pro-inflammatory metabolic signature in male mice at late adulthood

2023-06-25

Abstract excerpt

<h4>ABSTRACT</h4> Polybrominated diphenyl ethers (PBDEs) are a class of legacy flame retardants that bioaccumulate in the environment, raising global health concerns. The gut microbiome is an important regulator of liver including xenobiotic biotransformation, nutrient homeostasis, and immune regulation. Using bulk RNA-Seq, we recently showed that neonatal exposure to BDE-99, a human breast milk-enriched PBDE con...

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Literature Corpus work: 761c2c94-4dd8-59a8-b7f0-8d9bec0e9861
DOI: 10.1101/2023.06.22.546158

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Single cell transcriptomics unveiled that early life BDE-99 exposure reprogrammed the gut-liver axis to promote a pro-inflammatory metabolic signature in male mice at late adulthoodDOI 10.1101/2023.06.22.546158Read

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