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Investigation of Key Molecular Mechanisms of 6PPDQ in Breast Cancer Development and Progression through Network Toxicology and Computational Simulation

2026-03-27

Abstract excerpt

<title>Abstract</title> <p>Background The rapid expansion of tire manufacturing has led to widespread environmental contamination by 6PPD-quinone (6PPDQ). Although 6PPDQ exhibits well-documented toxicological properties, its mechanistic links to breast cancer pathogenesis remain unexplored. This study represents the first attempt to examine these associations using network toxicology approaches. Methods Putativ...

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Literature Corpus work
1ae02e20-c022-54f5-8353-302ec27e8b89
DOI
10.21203/rs.3.rs-9012385/v1
Open publication

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