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Blood pressure polygenic score, cardiorespiratory fitness and odds of dementia: the HUNT Study.

Age and ageing - 2 Jul 2026

Lerfald Maren, Øvretveit Karsten, Nilsen Tom Ivar Lund, Eldholm Rannveig Sakshaug, Grøtting Nora, Wolford Brooke N, Selbaek Geir, Ernstsen Linda

Abstract excerpt

High blood pressure (BP) is linked to an increased dementia risk. The role of sex and the impact of cardiorespiratory fitness (CRF) on the potential association between genetic predisposition to high blood pressure and dementia are less understood. Our aim was to investigate if there is an association between genetic predisposition to high systolic blood pressure (SBP) and occurrence of dementia in males and...

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Blood Pressure
Dementia
Genetic Risk Score
Hypertension
Logistic Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multifactorial Inheritance

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PMID: 42476555
DOI: 10.1093/ageing/afag214
PMCID: PMC13384636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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