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Article

Association of genetic predisposition to dyslipidemia and physical activity with incident dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jan 2026

Liang Yumei, Xie Siqi, Sheng Dandan, Ding Lan, Yang Ting, Jia Jianping

Abstract excerpt

INTRODUCTION: The association between genetic predisposition to dyslipidemia and dementia risk is inconsistent. It remains unknown whether a physically active lifestyle is associated with a lower dementia risk across different levels of this genetic predisposition. METHODS: We analyzed 198,448 White participants (aged ≥ 60 years) with a median 14.8-year follow-up in UK Biobank. We used Cox proportional hazards...

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Cholesterol, HDL
Cholesterol, LDL
Dementia
Dementia, Vascular
Dyslipidemias

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Risk Score

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PMID: 41499243
DOI: 10.1002/alz.71079
PMCID: PMC12778432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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