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Social Determinants of Health, Genetic Susceptibility, and Risk of Dementia: A Prospective Cohort Study.

American journal of preventive medicine - 1 Jul 2026

Chen Huan, Wang Xiao-Lin, Gao Jian, Li Chuan, Huang Qing-Mei, Zhong Wen-Fang, Xie Jia-Hao, Liu Wei, Liu Dan, Li Zhi-Hao, Mao Chen

Abstract excerpt

INTRODUCTION: The association between social determinants of health, genetic susceptibility, and dementia risk remains unclear. This study investigates their relationship and the potential mediation by chronic conditions. METHODS: Data from 225,598 UK Biobank participants (220,847 for genetic analyses), with an average age of 55.07 years and 51.10% female, were analyzed. The data were collected during 2006-2010...

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PMID: 41619950
DOI: 10.1016/j.amepre.2026.108294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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