Bayesian inference of haematopoietic stem/progenitor cell differentiation phenotypic manifolds and their bifurcation points using Gaussian processes and Gibbs sampling.

Abstract excerpt

Cell differentiation is a fundamental biological process, where cells progress through different stages of maturation to become specialised cell types. Understanding this process is important, and has led to the development of various mathematical models to represent cell behaviour during maturation. Advancements in these models are owed to researchers' ability to obtain high-throughput genome-scale single-cell...

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