Article

Single-cell RNA-Sequencing uncovers transcriptional states and fate decisions in haematopoiesis

2017-03-18

Abstract excerpt

<h4>ABSTRACT</h4> The success of marker-based approaches for dissecting haematopoiesis in mouse and human is reliant on the presence of well-defined cell-surface markers specific for diverse progenitor populations. An inherent problem with this approach is that the presence of specific cell surface markers does not directly reflect the transcriptional state of a cell. Here we used a marker-free approach to comput...

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Literature Corpus work: c6ca26ef-f195-5a06-bf75-04e8d0ec853d
DOI: 10.1101/117960

Open publication

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