Article

Hematopoietic differentiation is characterized by a transient peak of entropy at a single cell level

2021-04-30

Abstract excerpt

Hematopoietic differentiation has been metaphorically represented as linear trajectories with discrete steps from hematopoietic stem cells to mature cells. While the transcriptional state of cells at the beginning or at the end of these trajectories are well described from bulk analysis, what happens in the intermediate states has remained elusive until the use of single cell approaches. Applying Shannon entropy t...

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Literature Corpus work: 6cb2c66a-bac8-58e9-9d88-74283799932d
DOI: 10.1101/2021.04.30.442092

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