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New frameworks for hematopoiesis derived from single-cell genomics

10 Jul 2024

Abstract excerpt

ABSTRACT: Recent advancements in single-cell genomics have enriched our understanding of hematopoiesis, providing intricate details about hematopoietic stem cell biology, differentiation, and lineage commitment. Technological advancements have highlighted extensive heterogeneity of cell populations and continuity of differentiation routes. Nevertheless, intermediate "attractor" states signify structure in stem...

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PMID: 38985829
DOI: 10.1182/blood.2024024006

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